ASRV.Gamma_median — The median-discretized Gamma rate
heterogeneity model
Usage
ASRV.Gamma_median(submodel: DiscreteDist<CTMC<a>>,
n: Int, alpha: Double) → DiscreteDist<CTMC<a>>
Arguments
A default beginning with ~ specifies a prior
distribution.
-
submodel: -
The model being scaled
-
n: -
The number of equal-probability Gamma categories
-
Default:
4 -
alpha: -
The shape parameter for the Gamma distribution
-
Default:
~LogLaplace(6,2)
Description
This model uses equal-probability categories represented by their medians to approximate Gamma-distributed rates across sites. The rates are normalized to have mean one when applied to the substitution model.
Examples
GTR +> ASRV.Gamma_median(4) +> Inv
Citation
Yang, Ziheng (1994). Maximum likelihood phylogenetic estimation from DNA sequences with variable rates over sites: approximate methods. Journal of molecular evolution 39(3): 306--314. DOI: 10.1007/BF00160154